Experimental Study of Bone Response with BIC and Removal Torque Test.

Experimental Study of Bone Response to Hydroxyapatite Coating Implants: BIC and Removal Torque Test
By: Tae-Gwan Eom, Gyeo-Rok Jeon, Chang-Mo Jeong, Young-Kyun Kim, Su-Gwan Kim, In-Hee Cho, Yong-Seok Cho, Ji-Su Oh


The objective of this study was to evaluate the early osseointegration of hydroxyapatite (HA) coated implant versus resorbable blast media (RBM) and sand-blasted with alumina and acid etched (SA) surface tapered implants.

Materials & Methods:

Twelve adult male miniature pigs (Medi Kinetics Micropigs, Medi Kinetics Co., Ltd., Korea) were used in this study. The removal torque of implants placed in the tibia of miniature pigs was measured. For implants placed in the mandible, histomorphometric evaluation was performed for the evaluation of the bone-implant contact (BIC) ratio.


After 4, 8, and 12 weeks, removal torque values were increased. Among the 3 groups, the HA coated group showed the highest value (p < .05). When the HA surface, RBM, and SA surface group were compared at each time point, the HA group showed statistically significantly high removal torque value (RTV) values (p< .05). At 2 weeks, in comparison with RBM, SA showed an 11 % increase, and HA showed a 42 % increase; nonetheless, they were not statistically significant. At 4 weeks, the BIC ratio of HA was significantly higher than that of SA (p < .05). Nonetheless, RBM and SA were not significantly different (p > .05). At 8 weeks, the BIC of HA was shown to be significantly higher than RBM or SA (p < .05). Nonetheless, RBM and SA were not significantly different (p > .05).


The early osseointegration of HA coated implants was found to be excellent, and HA coated implants will be available in poor quality bone.


Fig. 1. Removal torque value graph.

Fig. 2. BIC ratio.


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